C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063065 Mapk3 10090 + 7:126759601-126765819 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050201 Mapk3-003 126759601-126764845 protein_coding
  ENSMUST00000057669 Mapk3-001 126759601-126765819 protein_coding
  ENSMUST00000091328 Mapk3-002 126760597-126765819 protein_coding
  ENSMUST00000135649 Mapk3-005 126763277-126764360 processed_transcript
  ENSMUST00000145965 Mapk3-004 126759834-126763159 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057669ENSMUST00000091328
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057669 101.306±12.85 94.585±18.74 82.724±1.21 40.569±24.15 72.122±16.03 243.356±29.32 29.291±6.77 71.698±3.11 25.395±4.76 205.271±21.80 11.064±0.85 86.602±34.22 35.114±39.37 75.910±37.57
ENSMUST00000091328 N/A 48.157±0.82 N/A N/A N/A 37.139±0.00 N/A N/A N/A N/A N/A 66.924±27.83 19.543±5.48 20.215±5.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WO CIL_0005WO_0002 CGP 7:126759601-126775643

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0001784 IMP phosphotyrosine binding
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004672 IDA protein kinase activity
GO:0004707 TAS MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005794 TAS Golgi apparatus
GO:0005829 IDA cytosol
GO:0005856 TAS cytoskeleton
GO:0005901 TAS caveola
GO:0005925 TAS focal adhesion
GO:0006351 IMP transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006975 IEA DNA damage induced protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0009887 IDA organ morphogenesis
GO:0015630 IEA microtubule cytoskeleton
GO:0016310 TAS phosphorylation
GO:0019233 IMP sensory perception of pain
GO:0019902 IEA phosphatase binding
GO:0030509 IEA BMP signaling pathway
GO:0031143 IDA pseudopodium
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032496 IDA response to lipopolysaccharide
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0033129 IEA positive regulation of histone phosphorylation
GO:0035066 IEA positive regulation of histone acetylation
GO:0038083 IEA peptidyl-tyrosine autophosphorylation
GO:0043330 IDA response to exogenous dsRNA
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051090 IMP regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 IDA cartilage development
GO:0051493 TAS regulation of cytoskeleton organization
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0070498 IEA interleukin-1-mediated signaling pathway
GO:0070849 ISS response to epidermal growth factor
GO:0071260 IEA cellular response to mechanical stimulus
GO:0072584 TAS caveolin-mediated endocytosis
GO:0090170 TAS regulation of Golgi inheritance
GO:2000641 TAS regulation of early endosome to late endosome transport
GO:2000657 IMP negative regulation of apolipoprotein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070573 mapk3 mitogen-activated protein kinase 3 protein_coding Danio_rerio
ENSG00000102882 MAPK3 mitogen-activated protein kinase 3 protein_coding Homo_sapiens

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