C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000057669 Mapk3-001 ENSMUSG00000063065 10090 + 7:126759601-126765819 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057669 101.306±12.85 94.585±18.74 82.724±1.21 40.569±24.15 72.122±16.03 243.356±29.32 29.291±6.77 71.698±3.11 25.395±4.76 205.271±21.80 11.064±0.85 86.602±34.22 35.114±39.37 75.910±37.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WO CIL_0005WO_0002 CGP 7:126759601-126775643

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0001784 IMP phosphotyrosine binding
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004672 IDA protein kinase activity
GO:0004707 TAS MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005794 TAS Golgi apparatus
GO:0005829 IDA:TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005901 TAS caveola
GO:0005925 TAS focal adhesion
GO:0006351 IMP transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006975 IEA DNA damage induced protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0009887 IDA organ morphogenesis
GO:0015630 IEA microtubule cytoskeleton
GO:0016310 TAS phosphorylation
GO:0019233 IMP sensory perception of pain
GO:0019902 IEA phosphatase binding
GO:0030509 IEA BMP signaling pathway
GO:0031143 IDA pseudopodium
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032496 IDA response to lipopolysaccharide
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0033129 IEA positive regulation of histone phosphorylation
GO:0035066 IEA positive regulation of histone acetylation
GO:0038083 IEA peptidyl-tyrosine autophosphorylation
GO:0043330 IDA response to exogenous dsRNA
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051090 IMP regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 IDA cartilage development
GO:0051493 TAS regulation of cytoskeleton organization
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0070498 IEA interleukin-1-mediated signaling pathway
GO:0070849 ISS response to epidermal growth factor
GO:0071260 IEA cellular response to mechanical stimulus
GO:0072584 TAS caveolin-mediated endocytosis
GO:0090170 TAS regulation of Golgi inheritance
GO:2000641 TAS regulation of early endosome to late endosome transport
GO:2000657 IMP negative regulation of apolipoprotein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000047248 nlk2-201 protein_coding Danio_rerio 0.000000004 68
ENSDART00000123937 nlk2-001 protein_coding Danio_rerio 0.000000004 68
ENST00000263025 MAPK3-001 protein_coding Homo_sapiens 0 1578
ENST00000322266 MAPK3-201 protein_coding Homo_sapiens 0 1050
ENST00000395199 MAPK3-006 protein_coding Homo_sapiens 0 1332
ENST00000395200 MAPK3-011 protein_coding Homo_sapiens 0 643
ENST00000395202 MAPK3-004 protein_coding Homo_sapiens 0 1031
ENST00000461737 MAPK3-012 nonsense_mediated_decay Homo_sapiens 0 460
ENST00000466521 MAPK3-002 nonsense_mediated_decay Homo_sapiens 0 1506
ENST00000473431 MAPK3-013 retained_intron Homo_sapiens 0 300
ENST00000478356 MAPK3-009 protein_coding Homo_sapiens 0 630
ENST00000483869 MAPK3-008 retained_intron Homo_sapiens 1e-20 104
ENST00000484663 MAPK3-003 protein_coding Homo_sapiens 0 1339
ENST00000490298 MAPK3-005 nonsense_mediated_decay Homo_sapiens 0 1273

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