C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dehydrogenase/reductase (SDR family) member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066026 Dhrs3 10090 + 4:144892827-144928209 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084184 Dhrs3-003 144893219-144927639 nonsense_mediated_decay
  ENSMUST00000105744 Dhrs3-002 144892827-144927642 protein_coding
  ENSMUST00000128926 Dhrs3-005 144893131-144919972 processed_transcript
  ENSMUST00000133265 Dhrs3-006 144918879-144919972 retained_intron
  ENSMUST00000142808 Dhrs3-004 144893137-144919898 protein_coding
  ENSMUST00000154208 Dhrs3-001 144893077-144928209 protein_coding
  ENSMUST00000171001 Dhrs3-201 144892827-144927645 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084184ENSMUST00000105744ENSMUST00000142808ENSMUST00000154208ENSMUST00000171001
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084184 13.937±5.67 10.921±1.92 24.903±2.67 1.629±0.34 12.907±4.31 12.121±1.97 9.087±0.90 18.608±1.97 14.150±11.50 17.650±6.72 2.755±0.99 17.492±3.23 7.305±3.38 1.319±0.22
ENSMUST00000105744 N/A N/A N/A 15.522±0.00 N/A N/A N/A N/A N/A N/A N/A 72.272±0.00 36.497±9.06 2.506±0.00
ENSMUST00000142808 N/A N/A N/A 3.779±0.00 N/A N/A N/A N/A N/A N/A N/A 30.623±0.00 9.196±2.48 0.650±0.00
ENSMUST00000154208 11.979±3.45 5.719±0.00 12.578±0.50 0.681±0.00 8.071±1.38 4.082±0.66 10.487±0.06 22.948±6.35 9.692±10.38 9.417±0.82 1.129±0.25 5.037±0.00 3.090±0.32 N/A
ENSMUST00000171001 78.450±29.65 51.900±14.44 71.295±3.28 3.833±1.36 63.160±11.50 26.765±5.22 32.403±1.72 107.665±14.05 37.430±26.61 58.667±13.05 4.907±0.98 54.939±27.02 13.954±3.26 2.872±0.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003MQ CIL_0003MQ_0002 CGP 4:144892827-145195005

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 IMP retinoid metabolic process
GO:0003151 IMP outflow tract morphogenesis
GO:0004745 IMP retinol dehydrogenase activity
GO:0016021 IEA integral component of membrane
GO:0030278 IMP regulation of ossification
GO:0042572 IEA retinol metabolic process
GO:0048387 IMP negative regulation of retinoic acid receptor signaling pathway
GO:0052650 IEA NADP-retinol dehydrogenase activity
GO:0055114 IEA oxidation-reduction process
GO:0060021 IMP palate development
GO:0060349 IMP bone morphogenesis
GO:0060411 IMP cardiac septum morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044803 dhrs3b dehydrogenase/reductase (SDR family) member 3b protein_coding Danio_rerio
ENSDARG00000044982 dhrs3a dehydrogenase/reductase (SDR family) member 3a protein_coding Danio_rerio
ENSG00000162496 DHRS3 dehydrogenase/reductase (SDR family) member 3 protein_coding Homo_sapiens

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