C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sortilin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068747 Sort1 10090 + 3:108284091-108361511 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102632 Sort1-001 108284091-108361511 protein_coding
  ENSMUST00000129755 Sort1-002 108355467-108356630 processed_transcript
  ENSMUST00000135636 Sort1-003 108345821-108357870 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102632ENSMUST00000135636
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102632 63.775±17.24 19.065±4.78 14.846±3.94 34.743±14.88 48.561±4.59 83.149±6.49 15.133±0.40 15.543±2.50 4.141±0.98 76.023±2.55 14.588±0.87 18.210±4.09 2.739±0.68 23.124±8.01
ENSMUST00000135636 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.788±3.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099A CIL_00099A_0002 VISTA 3:108089934-108692442
CIL_00098X CIL_00098X_0002 VISTA 3:108109603-108712500

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005764 IEA lysosome
GO:0005769 IEA early endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005905 IEA coated pit
GO:0006895 IEA Golgi to endosome transport
GO:0006897 IEA endocytosis
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008333 IEA endosome to lysosome transport
GO:0008625 IEA extrinsic apoptotic signaling pathway via death domain receptors
GO:0009986 IEA cell surface
GO:0010465 IEA nerve growth factor receptor activity
GO:0010468 IEA regulation of gene expression
GO:0014902 IMP myotube differentiation
GO:0016021 IEA integral component of membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016050 IMP vesicle organization
GO:0019899 IEA enzyme binding
GO:0030136 IEA clathrin-coated vesicle
GO:0030140 IDA trans-Golgi network transport vesicle
GO:0030379 IEA neurotensin receptor activity, non-G-protein coupled
GO:0032509 IEA endosome transport via multivesicular body sorting pathway
GO:0032868 IMP response to insulin
GO:0038180 IEA nerve growth factor signaling pathway
GO:0046323 IMP glucose import
GO:0048011 IEA neurotrophin TRK receptor signaling pathway
GO:0048227 IEA plasma membrane to endosome transport
GO:0048406 IEA nerve growth factor binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051005 IEA negative regulation of lipoprotein lipase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029402 sort1a sortilin 1a protein_coding Danio_rerio
ENSDARG00000056252 sort1b sortilin 1b protein_coding Danio_rerio
ENSG00000134243 SORT1 sortilin 1 protein_coding Homo_sapiens

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