C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, pyrin domain containing 1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000069830 Nlrp1a 10090 - 11:71092236-71144704 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048514 Nlrp1a-002 71092236-71142366 protein_coding
  ENSMUST00000108518 Nlrp1a-001 71092236-71144704 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048514ENSMUST00000108518
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048514 N/A 0.011±0.00 N/A 0.067±0.04 0.010±0.00 N/A N/A N/A N/A N/A 0.017±0.01 N/A N/A
ENSMUST00000108518 0.064±0.02 0.027±0.01 0.067±0.08 0.102±0.02 0.016±0.01 0.023±0.01 0.038±0.01 0.025±0.01 0.036±0.04 0.018±0.01 0.050±0.03 0.033±0.02 0.033±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002G8 CIL_0002G8_0002 CGP 11:71019611-71144704

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 ISS nucleus
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0019899 ISS enzyme binding
GO:0032495 IDA response to muramyl dipeptide
GO:0042742 IDA defense response to bacterium
GO:0042981 IEA regulation of apoptotic process
GO:0050718 IDA positive regulation of interleukin-1 beta secretion
GO:0051402 ISS neuron apoptotic process
GO:0097300 IDA programmed necrotic cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088074 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000088236 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000094305 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000096064 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000096067 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSG00000091592 NLRP1 NLR family, pyrin domain containing 1 protein_coding Homo_sapiens

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