C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thioredoxin reductase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000075704 Txnrd2 10090 + 16:18426417-18479073 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000115604 Txnrd2-002 18426433-18456468 protein_coding
  ENSMUST00000115605 Txnrd2-011 18426417-18479070 nonsense_mediated_decay
  ENSMUST00000115606 Txnrd2-001 18426417-18479073 protein_coding
  ENSMUST00000126330 Txnrd2-009 18471821-18472886 processed_transcript
  ENSMUST00000126778 Txnrd2-003 18428697-18437810 retained_intron
  ENSMUST00000131303 Txnrd2-004 18426512-18437812 retained_intron
  ENSMUST00000138310 Txnrd2-006 18440801-18442438 processed_transcript
  ENSMUST00000144233 Txnrd2-005 18428925-18441812 processed_transcript
  ENSMUST00000149937 Txnrd2-007 18452039-18472249 processed_transcript
  ENSMUST00000153457 Txnrd2-008 18452045-18472886 processed_transcript
  ENSMUST00000156604 Txnrd2-010 18471851-18472249 retained_intron
  ENSMUST00000177856 Txnrd2-201 18426438-18479067 protein_coding
  ENSMUST00000178093 Txnrd2-202 18426438-18479067 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartLiverMuscleOvaryPlacentaTestisENSMUST00000115606ENSMUST00000144233
Transcript ID Adrenal Brain Breast Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000115606 58.383±5.95 8.640±0.00 17.310±0.00 17.738±2.45 50.183±16.78 8.987±1.14 12.281±3.55 12.137±0.89 2.507±0.84
ENSMUST00000144233 N/A N/A N/A N/A 136.903±33.85 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095F CIL_00095F_0002 VISTA 16:18254168-18857637
CIL_00099J CIL_00099J_0002 VISTA 16:18285741-18886132
CIL_0008BW CIL_0008BW_0002 VISTA 16:18293232-18893684

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000305 TAS response to oxygen radical
GO:0004791 ISS thioredoxin-disulfide reductase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0007507 IMP heart development
GO:0030097 IMP hemopoiesis
GO:0045454 IEA cell redox homeostasis
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075923 TXNRD2 (1 of 2) thioredoxin reductase 2 protein_coding Danio_rerio
ENSDARG00000094470 txnrd2 thioredoxin reductase 2 protein_coding Danio_rerio
ENSG00000184470 TXNRD2 thioredoxin reductase 2 protein_coding Homo_sapiens

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