C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thioredoxin reductase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184470 TXNRD2 9606 - 22:19875517-19941992 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334363 TXNRD2-201 19894258-19941992 protein_coding
  ENST00000400518 TXNRD2-004 19875517-19932553 protein_coding
  ENST00000400519 TXNRD2-012 19875547-19941803 protein_coding
  ENST00000400521 TXNRD2-003 19875522-19941810 protein_coding
  ENST00000400525 TXNRD2-006 19875522-19941818 protein_coding
  ENST00000462330 TXNRD2-017 19875522-19881369 protein_coding
  ENST00000462843 TXNRD2-019 19875692-19881154 protein_coding
  ENST00000471835 TXNRD2-014 19911258-19915837 retained_intron
  ENST00000474308 TXNRD2-007 19875519-19941807 protein_coding
  ENST00000475995 TXNRD2-016 19895016-19898130 protein_coding
  ENST00000484672 TXNRD2-015 19910935-19918221 processed_transcript
  ENST00000485358 TXNRD2-018 19875641-19881164 protein_coding
  ENST00000487165 TXNRD2-010 19875522-19884504 retained_intron
  ENST00000491939 TXNRD2-005 19894260-19933526 protein_coding
  ENST00000494454 TXNRD2-008 19875518-19916366 retained_intron
  ENST00000495655 TXNRD2-011 19875524-19881347 retained_intron
  ENST00000496729 TXNRD2-013 19914900-19941808 retained_intron
  ENST00000542719 TXNRD2-020 19875520-19938179 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryTestisENST00000400521ENST00000400525ENST00000542719
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENST00000400521 10.603±0.00 N/A 15.875±0.00 17.052±0.00 7.051±5.82 7.164±6.45 24.340±0.00 21.657±0.00 N/A 28.705±0.32 17.115±0.00
ENST00000400525 N/A N/A N/A N/A N/A N/A N/A 19.913±0.00 N/A N/A N/A
ENST00000542719 N/A 1.507±0.00 N/A N/A N/A N/A N/A N/A 1.655±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BW CIL_0008BW_0001 VISTA 22:19453681-20054184
CIL_00099J CIL_00099J_0001 VISTA 22:19461833-20062532
CIL_00095F CIL_00095F_0001 VISTA 22:19497462-20100487

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004791 IEA thioredoxin-disulfide reductase activity
GO:0005515 IEA protein binding
GO:0005739 IEA mitochondrion
GO:0007507 IEA heart development
GO:0008033 IEA tRNA processing
GO:0016491 IEA oxidoreductase activity
GO:0016668 IEA oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0030097 IEA hemopoiesis
GO:0045454 IEA cell redox homeostasis
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075923 TXNRD2 (1 of 2) thioredoxin reductase 2 protein_coding Danio_rerio
ENSDARG00000094470 txnrd2 thioredoxin reductase 2 protein_coding Danio_rerio
ENSMUSG00000075704 Txnrd2 thioredoxin reductase 2 protein_coding Mus_musculus

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