C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000078652 Psme3 10090 + 11:101316213-101323537 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019470 Psme3-001 101316213-101323537 protein_coding
  ENSMUST00000127998 Psme3-004 101317023-101320024 processed_transcript
  ENSMUST00000131170 Psme3-005 101319834-101322099 processed_transcript
  ENSMUST00000142640 Psme3-002 101316213-101320008 protein_coding
  ENSMUST00000151385 Psme3-003 101316977-101320594 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019470ENSMUST00000131170ENSMUST00000151385
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019470 32.260±1.31 34.025±6.03 29.321±2.18 38.247±17.10 29.666±6.70 25.294±3.36 22.407±5.13 30.789±7.80 62.019±46.40 23.997±0.89 18.466±1.01 29.467±6.41 34.120±15.48 27.107±11.79
ENSMUST00000131170 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.526±0.00 13.499±0.00
ENSMUST00000151385 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 34.289±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005S9 CIL_0005S9_0002 CGP 11:101285952-101323537
CIL_0004MA CIL_0004MA_0002 CGP 11:101316213-101329702

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002039 ISS p53 binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0007049 IEA cell cycle
GO:0008537 IEA proteasome activator complex
GO:0010950 IEA positive regulation of endopeptidase activity
GO:0016020 IEA membrane
GO:0061133 IEA endopeptidase activator activity
GO:0061136 IEA regulation of proteasomal protein catabolic process
GO:0097371 ISS MDM2/MDM4 family protein binding
GO:2001237 ISS negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012234 psme3 proteasome activator subunit 3 protein_coding Danio_rerio
ENSG00000131467 PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) protein_coding Homo_sapiens

Loading