C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific methyltransferase 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002095 Kmt2a-201 ENSMUSG00000002028 10090 - 9:44803355-44881274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002095
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002095 1.548±0.44 1.603±0.24 1.565±0.25 5.320±2.92 3.642±3.50 2.072±1.18 1.370±0.68 1.597±1.21 0.872±0.52 1.421±0.24 2.062±0.81 4.054±2.84 3.633±3.03 0.426±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0002 VISTA 9:44577224-45180192

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006306 IMP DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0006461 IEA protein complex assembly
GO:0008270 ISS zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0032411 IEA positive regulation of transporter activity
GO:0035097 ISS histone methyltransferase complex
GO:0035162 IMP embryonic hemopoiesis
GO:0042800 ISS histone methyltransferase activity (H3-K4 specific)
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043984 ISS histone H4-K16 acetylation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045322 ISS unmethylated CpG binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0051568 ISS histone H3-K4 methylation
GO:0051569 IMP regulation of histone H3-K4 methylation
GO:0070577 ISS lysine-acetylated histone binding
GO:0071339 ISS MLL1 complex
GO:0080182 IEA histone H3-K4 trimethylation
GO:2001040 IEA positive regulation of cellular response to drug

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000104525 kmt2a-201 protein_coding Danio_rerio 0 843
ENSDART00000148840 kmt2a-001 protein_coding Danio_rerio 0 843
ENST00000389506 KMT2A-015 protein_coding Homo_sapiens 0 15560
ENST00000392873 KMT2A-017 protein_coding Homo_sapiens 0 785
ENST00000420751 KMT2A-004 processed_transcript Homo_sapiens 5e-40 167
ENST00000525408 KMT2A-014 retained_intron Homo_sapiens 0 1116
ENST00000527839 KMT2A-013 retained_intron Homo_sapiens 0 667
ENST00000527869 KMT2A-016 protein_coding Homo_sapiens 0 322
ENST00000528278 KMT2A-005 retained_intron Homo_sapiens 0 1166
ENST00000529852 KMT2A-006 protein_coding Homo_sapiens 0 357
ENST00000531904 KMT2A-002 protein_coding Homo_sapiens 0 4927
ENST00000532204 KMT2A-010 protein_coding Homo_sapiens 0 357
ENST00000533790 KMT2A-007 protein_coding Homo_sapiens 0 817
ENST00000534085 KMT2A-009 retained_intron Homo_sapiens 3e-28 128
ENST00000534358 KMT2A-001 protein_coding Homo_sapiens 0 15520

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