C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific methyltransferase 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389506 KMT2A-015 ENSG00000118058 9606 + 11:118436513-118523917 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartKidneyLiverLungMuscleOvaryENST00000389506
Transcript ID Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENST00000389506 4.558±0.00 1.198±0.00 1.138±0.00 1.575±0.00 4.762±0.00 2.213±0.37 1.523±0.20 2.983±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0001 VISTA 11:118137591-118740525

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003680 NAS AT DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006461 IDA protein complex assembly
GO:0006915 IEA apoptotic process
GO:0008270 IDA:IEA zinc ion binding
GO:0032411 IMP positive regulation of transporter activity
GO:0035097 IDA:IEA histone methyltransferase complex
GO:0035162 TAS embryonic hemopoiesis
GO:0042800 IMP:IEA histone methyltransferase activity (H3-K4 specific)
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043984 IMP histone H4-K16 acetylation
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045322 IDA unmethylated CpG binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051568 IMP:IEA histone H3-K4 methylation
GO:0070577 IDA lysine-acetylated histone binding
GO:0071339 IDA MLL1 complex
GO:0080182 IDA histone H3-K4 trimethylation
GO:2001040 IMP positive regulation of cellular response to drug

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002095 Kmt2a-201 protein_coding Mus_musculus 0 15560
ENSMUST00000114689 Kmt2a-001 protein_coding Mus_musculus 0 15520
ENSMUST00000152241 Kmt2a-003 nonsense_mediated_decay Mus_musculus 0 5118
ENSMUST00000128768 Kmt2a-002 protein_coding Mus_musculus 0 4927
ENSMUST00000138119 Kmt2a-004 nonsense_mediated_decay Mus_musculus 0 2132
ENSMUST00000131002 Kmt2b-002 protein_coding Mus_musculus 0 368
ENSMUST00000108154 Kmt2b-001 protein_coding Mus_musculus 0 368
ENSMUST00000006470 Kmt2b-003 protein_coding Mus_musculus 0 368

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