C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2B, subunit 5 epsilon
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003320 Eif2b5-001 ENSMUSG00000003235 10090 + 16:20498817-20509955 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003320
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003320 9.545±2.29 16.727±5.59 2.504±0.00 16.958±0.04 10.376±2.41 9.238±3.21 3.601±0.31 9.531±2.34 3.735±1.69 6.353±3.94 8.832±3.05 9.930±4.50 18.786±8.32 11.378±6.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0002 CGP 16:20498817-20532520

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001541 ISS ovarian follicle development
GO:0003743 ISS translation initiation factor activity
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005851 ISS eukaryotic translation initiation factor 2B complex
GO:0006413 ISS translational initiation
GO:0006417 IEA regulation of translation
GO:0009408 ISS response to heat
GO:0009749 ISS response to glucose
GO:0014002 ISS astrocyte development
GO:0014003 ISS oligodendrocyte development
GO:0031369 IEA translation initiation factor binding
GO:0032057 IEA negative regulation of translational initiation in response to stress
GO:0034976 ISS response to endoplasmic reticulum stress
GO:0035690 ISS cellular response to drug
GO:0042552 ISS myelination
GO:0043434 ISS response to peptide hormone
GO:0043547 ISS positive regulation of GTPase activity
GO:0045948 ISS positive regulation of translational initiation
GO:0048708 ISS astrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000273783 EIF2B5-001 protein_coding Homo_sapiens 0 2423
ENST00000432569 EIF2B5-003 protein_coding Homo_sapiens 0 324
ENST00000432982 EIF2B5-006 nonsense_mediated_decay Homo_sapiens 0 385
ENST00000444495 EIF2B5-017 protein_coding Homo_sapiens 0 2311
ENST00000465218 EIF2B5-005 retained_intron Homo_sapiens 0 540
ENST00000468748 EIF2B5-009 retained_intron Homo_sapiens 5e-39 165
ENST00000479250 EIF2B5-012 retained_intron Homo_sapiens 0 364
ENST00000479833 EIF2B5-016 processed_transcript Homo_sapiens 0 453
ENST00000481054 EIF2B5-004 retained_intron Homo_sapiens 0 1120
ENST00000491144 EIF2B5-002 retained_intron Homo_sapiens 0 1574
ENST00000492773 EIF2B5-011 processed_transcript Homo_sapiens 0 505
ENST00000493740 EIF2B5-010 retained_intron Homo_sapiens 0 412

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