C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000273783 EIF2B5-001 ENSG00000145191 9606 + 3:184135264-184145310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000273783
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000273783 11.438±0.00 0.808±0.00 5.288±2.01 5.083±3.50 6.598±3.56 5.807±4.80 8.186±6.74 8.185±0.00 8.392±0.00 11.854±8.27 11.554±4.87 13.799±5.00 6.206±2.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001541 IMP ovarian follicle development
GO:0003743 NAS translation initiation factor activity
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005851 IDA eukaryotic translation initiation factor 2B complex
GO:0006412 TAS translation
GO:0006413 IDA translational initiation
GO:0006417 IEA regulation of translation
GO:0009408 ISS response to heat
GO:0009749 ISS response to glucose
GO:0010467 TAS gene expression
GO:0014002 IMP astrocyte development
GO:0014003 IMP oligodendrocyte development
GO:0031369 ISS translation initiation factor binding
GO:0032057 ISS negative regulation of translational initiation in response to stress
GO:0034976 IMP response to endoplasmic reticulum stress
GO:0035690 IDA cellular response to drug
GO:0042552 IMP myelination
GO:0043434 ISS response to peptide hormone
GO:0043547 ISS positive regulation of GTPase activity
GO:0044267 TAS cellular protein metabolic process
GO:0045948 ISS positive regulation of translational initiation
GO:0048708 IMP astrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003320 Eif2b5-001 protein_coding Mus_musculus 0 2423

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