C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003612 Dusp3-001 ENSMUSG00000003518 10090 - 11:101971143-101984799 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000003612
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000003612 17.905±4.40 24.563±1.68 20.180±0.78 5.436±3.95 15.925±1.88 14.599±1.83 15.432±1.02 10.267±1.44 3.607±1.25 33.234±6.48 28.602±1.19 12.132±3.88 5.049±1.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000996 CIL_000996_0002 VISTA 11:101501412-102102123
CIL_00090X CIL_00090X_0002 VISTA 11:101529827-102131014
CIL_000997 CIL_000997_0002 VISTA 11:101567301-102168287
CIL_0001CB CIL_0001CB_0002 CGP 11:101962458-101987013
CIL_00059Q CIL_00059Q_0002 CGP 11:101971143-101992264

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004721 IDA phosphoprotein phosphatase activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005829 IBA cytosol
GO:0006470 IDA protein dephosphorylation
GO:0008138 IDA protein tyrosine/serine/threonine phosphatase activity
GO:0033549 IBA MAP kinase phosphatase activity
GO:0045931 IBA positive regulation of mitotic cell cycle
GO:0046329 IBA negative regulation of JNK cascade
GO:0050860 IBA negative regulation of T cell receptor signaling pathway
GO:0050868 IBA negative regulation of T cell activation
GO:0070373 IBA negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000226004 DUSP3-001 protein_coding Homo_sapiens 0 798
ENST00000590342 DUSP3-002 nonsense_mediated_decay Homo_sapiens 0 566
ENST00000590753 DUSP3-004 protein_coding Homo_sapiens 0 303
ENST00000590935 DUSP3-003 protein_coding Homo_sapiens 0 309

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