C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AP2 associated kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003710 Aak1-003 ENSMUSG00000057230 10090 + 6:86850053-86991864 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLiverMuscleENSMUST00000003710
Transcript ID Brain Breast Liver Muscle
ENSMUST00000003710 9.184±0.56 0.442±0.00 0.210±0.03 0.181±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005112 ISS Notch binding
GO:0005524 IEA ATP binding
GO:0005905 IEA coated pit
GO:0006468 ISS protein phosphorylation
GO:0006897 IEA endocytosis
GO:0019897 ISS extrinsic component of plasma membrane
GO:0030136 ISS clathrin-coated vesicle
GO:0031252 ISS cell leading edge
GO:0032880 ISS regulation of protein localization
GO:0035612 ISS AP-2 adaptor complex binding
GO:0043195 ISS terminal bouton
GO:0045747 ISS positive regulation of Notch signaling pathway
GO:0046777 ISS protein autophosphorylation
GO:0050821 ISS protein stabilization
GO:2000369 ISS regulation of clathrin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000339092 AAK1-201 protein_coding Homo_sapiens 0 2612
ENST00000406297 AAK1-002 protein_coding Homo_sapiens 0 1980
ENST00000409068 AAK1-011 protein_coding Homo_sapiens 0 1980
ENST00000409085 AAK1-001 protein_coding Homo_sapiens 0 2606
ENST00000470281 AAK1-006 processed_transcript Homo_sapiens 0 488
ENST00000489327 AAK1-005 retained_intron Homo_sapiens 0 1186
ENST00000495836 AAK1-003 retained_intron Homo_sapiens 0 514
ENST00000606389 AAK1-012 protein_coding Homo_sapiens 0 486
ENST00000623317 AAK1-013 protein_coding Homo_sapiens 0 351
ENST00000624900 AAK1-014 protein_coding Homo_sapiens 0 318

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