C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AP2 associated kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409085 AAK1-001 ENSG00000115977 9606 - 2:69467787-69643717 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartENST00000409085
Transcript ID Brain Heart
ENST00000409085 7.730±1.35 1.118±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YR CIL_0000YR_0002 CGP 2:69457995-69826464

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005112 IDA Notch binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005905 IEA coated pit
GO:0006468 IDA:IEA protein phosphorylation
GO:0006897 IEA endocytosis
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019897 ISS extrinsic component of plasma membrane
GO:0030136 ISS clathrin-coated vesicle
GO:0031252 ISS cell leading edge
GO:0032880 IDA regulation of protein localization
GO:0035612 IDA AP-2 adaptor complex binding
GO:0043195 ISS terminal bouton
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0046777 ISS protein autophosphorylation
GO:0050821 IDA protein stabilization
GO:2000369 IMP regulation of clathrin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000089519 Aak1-001 protein_coding Mus_musculus 0 2671
ENSMUST00000003710 Aak1-003 protein_coding Mus_musculus 0 2606
ENSMUST00000113668 Aak1-002 protein_coding Mus_musculus 0 1631

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