C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth factor receptor bound protein 2-associated protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000004622 Gab2-201 ENSMUSG00000004508 10090 + 7:97081751-97308940 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004622
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004622 8.892±0.97 2.880±0.54 7.276±0.49 6.938±3.24 4.692±1.11 3.348±1.00 4.178±0.08 4.288±0.42 0.893±0.57 7.972±1.19 0.969±0.13 21.463±2.53 9.124±2.98 7.294±2.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PZ CIL_0002PZ_0002 CGP 7:96951505-97308940

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005068 IEA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 IDA integrin-mediated signaling pathway
GO:0008284 IEA positive regulation of cell proliferation
GO:0016477 IDA cell migration
GO:0030316 IEA osteoclast differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000113515 gab2-001 protein_coding Danio_rerio 0 259
ENST00000340149 GAB2-002 protein_coding Homo_sapiens 0 1458
ENST00000361507 GAB2-001 protein_coding Homo_sapiens 0 1624
ENST00000400588 GAB4-001 protein_coding Homo_sapiens 0 366
ENST00000464363 NELFCD-006 retained_intron Homo_sapiens 0.000001 58
ENST00000465611 GAB4-002 nonsense_mediated_decay Homo_sapiens 0 316
ENST00000523144 GAB4-003 processed_transcript Homo_sapiens 0 316
ENST00000526030 GAB2-004 processed_transcript Homo_sapiens 0 429
ENST00000528329 GAB2-007 processed_transcript Homo_sapiens 0 484
ENST00000528886 GAB2-003 protein_coding Homo_sapiens 0 566
ENST00000530915 GAB2-005 protein_coding Homo_sapiens 0 477
ENST00000534823 GAB2-006 retained_intron Homo_sapiens 0 579

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