C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: amyloid beta (A4) precursor-like protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006828 Aplp1-201 ENSMUSG00000006651 10090 - 7:30434981-30445582 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006828 1.786±0.79 19.976±4.18 2.109±0.17 324.214±171.98 1.737±0.77 19.984±1.68 1.519±0.12 5.547±0.51 1.517±1.49 3.860±0.76 0.345±0.11 2.755±1.27 7.054±2.89 3.424±0.41

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005794 IDA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006378 IDA mRNA polyadenylation
GO:0006417 IDA regulation of translation
GO:0006897 IEA endocytosis
GO:0006915 IEA apoptotic process
GO:0007155 IEA cell adhesion
GO:0008201 IEA heparin binding
GO:0016020 IDA membrane
GO:0016021 TAS integral component of membrane
GO:0030198 IGI extracellular matrix organization
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0030900 IGI forebrain development
GO:0031694 IEA alpha-2A adrenergic receptor binding
GO:0031695 IEA alpha-2B adrenergic receptor binding
GO:0031696 IEA alpha-2C adrenergic receptor binding
GO:0042802 IEA identical protein binding
GO:0046914 IEA transition metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0071874 IEA cellular response to norepinephrine stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000221891 APLP1-002 protein_coding Homo_sapiens 0 2327
ENST00000537454 APLP1-001 protein_coding Homo_sapiens 0 2043
ENST00000586861 APLP1-003 protein_coding Homo_sapiens 0 2032
ENST00000587274 APLP1-009 protein_coding Homo_sapiens 0 811
ENST00000590561 APLP1-004 nonsense_mediated_decay Homo_sapiens 0 1916
ENST00000591165 APLP1-012 processed_transcript Homo_sapiens 2.8026e-45 185
ENST00000592316 APLP1-011 protein_coding Homo_sapiens 0 1020

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