C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: amyloid beta (A4) precursor-like protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000221891 APLP1-002 ENSG00000105290 9606 + 19:35868445-35879788 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLungOvaryPlacentaENST00000221891
Transcript ID Adipose Brain Breast Colon Heart Lung Ovary Placenta
ENST00000221891 0.330±0.00 143.545±0.00 0.419±0.00 0.975±0.00 3.559±0.00 1.081±0.00 1.330±0.00 1.184±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005604 TAS basement membrane
GO:0005794 IEA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006378 IEA mRNA polyadenylation
GO:0006417 IEA regulation of translation
GO:0006897 IEA endocytosis
GO:0006915 IEA apoptotic process
GO:0007155 IEA cell adhesion
GO:0007193 IC adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0008201 IEA heparin binding
GO:0009887 TAS organ morphogenesis
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030198 IEA extracellular matrix organization
GO:0030818 IDA negative regulation of cAMP biosynthetic process
GO:0030900 IEA forebrain development
GO:0031694 IPI alpha-2A adrenergic receptor binding
GO:0031695 IPI alpha-2B adrenergic receptor binding
GO:0031696 IPI alpha-2C adrenergic receptor binding
GO:0042802 IPI identical protein binding
GO:0046914 IEA transition metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0071874 IDA cellular response to norepinephrine stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000006828 Aplp1-201 protein_coding Mus_musculus 0 2327
ENSDART00000019920 aplp1-201 protein_coding Danio_rerio 2e-39 169

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