C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transmembrane serine protease 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000017086 Tmprss6-201 ENSMUSG00000016942 10090 - 15:78439668-78468634 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017086
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017086 0.559±0.20 1.718±0.18 0.432±0.00 0.070±0.00 0.713±0.44 0.089±0.04 0.018±0.01 1.587±0.54 108.408±90.92 0.149±0.06 0.042±0.02 1.021±0.50 1.048±0.93 0.053±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036O CIL_00036O_0002 CGP 15:78428564-78468634
CIL_00036P CIL_00036P_0002 CGP 15:78439668-78495066

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004252 ISS serine-type endopeptidase activity
GO:0005886 ISO plasma membrane
GO:0006508 ISS proteolysis
GO:0016021 ISS integral component of membrane
GO:0030514 IGI negative regulation of BMP signaling pathway
GO:0042730 ISS fibrinolysis
GO:0055072 IMP iron ion homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000346753 TMPRSS6-003 protein_coding Homo_sapiens 0 2289
ENST00000381792 TMPRSS6-201 protein_coding Homo_sapiens 0 1989
ENST00000406725 TMPRSS6-001 protein_coding Homo_sapiens 0 2289
ENST00000406856 TMPRSS6-002 protein_coding Homo_sapiens 0 1989
ENST00000423761 TMPRSS6-005 protein_coding Homo_sapiens 0 285
ENST00000442782 TMPRSS6-004 protein_coding Homo_sapiens 0 878

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