C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho-associated coiled-coil containing protein kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020904 Rock2-201 ENSMUSG00000020580 10090 + 12:16894978-16988274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020904
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020904 6.600±0.99 3.709±0.66 18.660±3.41 19.503±16.72 5.541±0.81 5.698±1.11 5.869±2.13 3.232±1.10 2.041±1.40 6.769±3.02 6.549±2.86 8.095±7.60 19.806±11.45 1.988±1.46

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001843 IGI neural tube closure
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0007266 ISO Rho protein signal transduction
GO:0008625 IGI extrinsic apoptotic signaling pathway via death domain receptors
GO:0010825 IMP positive regulation of centrosome duplication
GO:0016525 IEA negative regulation of angiogenesis
GO:0017048 IEA Rho GTPase binding
GO:0030036 IGI actin cytoskeleton organization
GO:0031616 IDA spindle pole centrosome
GO:0036464 IEA cytoplasmic ribonucleoprotein granule
GO:0044822 IEA poly(A) RNA binding
GO:0045616 IEA regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0048813 IGI dendrite morphogenesis
GO:0051298 IEA centrosome duplication

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261535 ROCK2-008 nonsense_mediated_decay Homo_sapiens 0 1899
ENST00000315872 ROCK2-001 protein_coding Homo_sapiens 0 5729
ENST00000399799 ROCK1-001 protein_coding Homo_sapiens 0 734
ENST00000401753 ROCK2-006 protein_coding Homo_sapiens 0 4636
ENST00000431087 ROCK2-007 protein_coding Homo_sapiens 0 553
ENST00000460262 ROCK2-004 retained_intron Homo_sapiens 0 222
ENST00000462366 ROCK2-005 processed_transcript Homo_sapiens 0 586
ENST00000493096 ROCK2-003 retained_intron Homo_sapiens 0 392
ENST00000616279 ROCK2-201 protein_coding Homo_sapiens 0 5701

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