C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FK506 binding protein 1b
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020964 Fkbp1b-201 ENSMUSG00000020635 10090 - 12:4833175-4841595 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020964
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020964 2.246±0.69 3.488±1.50 3.821±0.67 9.210±1.41 3.090±0.83 3.150±1.42 0.618±0.13 0.982±0.10 2.326±2.46 4.873±1.19 0.160±0.09 2.147±1.07 2.185±1.15 0.268±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JZ CIL_0003JZ_0002 CGP 12:4833175-4856925

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0002027 IMP regulation of heart rate
GO:0003755 IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IEA cytoplasm
GO:0006939 IMP smooth muscle contraction
GO:0007204 IMP positive regulation of cytosolic calcium ion concentration
GO:0009749 IMP response to glucose
GO:0010033 IEA response to organic substance
GO:0010459 IMP negative regulation of heart rate
GO:0010880 IMP regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IMP regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014808 IMP release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IEA membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019227 IMP neuronal action potential propagation
GO:0019855 IBA calcium channel inhibitor activity
GO:0030018 IEA Z disc
GO:0030073 IMP insulin secretion
GO:0030551 IEA cyclic nucleotide binding
GO:0032513 IEA negative regulation of protein phosphatase type 2B activity
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0033197 IEA response to vitamin E
GO:0034704 IDA calcium channel complex
GO:0042098 IMP T cell proliferation
GO:0042542 IEA response to hydrogen peroxide
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044325 IPI ion channel binding
GO:0048680 IEA positive regulation of axon regeneration
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0051280 IBA negative regulation of release of sequestered calcium ion into cytosol
GO:0051284 IEA positive regulation of sequestering of calcium ion
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0051775 IEA response to redox state
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 IEA negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0061077 IBA chaperone-mediated protein folding
GO:0061179 IMP negative regulation of insulin secretion involved in cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000380986 FKBP1B-001 protein_coding Homo_sapiens 0 948
ENST00000380991 FKBP1B-002 protein_coding Homo_sapiens 0 527
ENST00000421839 FKBP1B-004 nonsense_mediated_decay Homo_sapiens 0 691
ENST00000438630 FKBP1B-003 nonsense_mediated_decay Homo_sapiens 0 527
ENST00000452109 FKBP1B-006 protein_coding Homo_sapiens 0 688
ENST00000453731 MFSD2B-004 nonsense_mediated_decay Homo_sapiens 0 333
ENST00000496149 FKBP1B-005 retained_intron Homo_sapiens 0 497

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