C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FK506 binding protein 1B, 12.6 kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380986 FKBP1B-001 ENSG00000119782 9606 + 2:24049714-24063681 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380986
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380986 1.773±0.00 0.196±0.00 10.052±6.05 0.495±0.11 0.834±0.61 0.028±0.00 4.406±0.00 0.788±0.49 5.939±0.00 0.838±0.00 1.488±0.60 2.037±0.67 2.202±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IEA:IDA protein peptidyl-prolyl isomerization
GO:0002027 IEA regulation of heart rate
GO:0003755 IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IPI receptor binding
GO:0005219 TAS ryanodine-sensitive calcium-release channel activity
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IDA cytoplasm
GO:0005829 IC cytosol
GO:0006457 IEA protein folding
GO:0006458 TAS 'de novo' protein folding
GO:0006939 IEA smooth muscle contraction
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010459 ISS negative regulation of heart rate
GO:0010880 IDA regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 ISS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014808 IEA release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IDA membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0019227 IEA neuronal action potential propagation
GO:0019855 IDA calcium channel inhibitor activity
GO:0022417 TAS protein maturation by protein folding
GO:0030018 IDA Z disc
GO:0030073 IEA insulin secretion
GO:0030551 IEA cyclic nucleotide binding
GO:0032513 IDA negative regulation of protein phosphatase type 2B activity
GO:0033017 IBA sarcoplasmic reticulum membrane
GO:0033197 IEA response to vitamin E
GO:0034704 IDA calcium channel complex
GO:0035584 TAS calcium-mediated signaling using intracellular calcium source
GO:0042026 TAS protein refolding
GO:0042098 IEA T cell proliferation
GO:0042542 IEA response to hydrogen peroxide
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044325 ISS ion channel binding
GO:0048680 IEA positive regulation of axon regeneration
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0051280 IDA negative regulation of release of sequestered calcium ion into cytosol
GO:0051284 IDA positive regulation of sequestering of calcium ion
GO:0051480 IDA cytosolic calcium ion homeostasis
GO:0051775 IDA response to redox state
GO:0060314 IDA regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 IDA negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0061077 IBA chaperone-mediated protein folding
GO:0061179 IEA negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070588 TAS calcium ion transmembrane transport
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020964 Fkbp1b-201 protein_coding Mus_musculus 0 948

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