C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022100 Slc6a3-201 ENSMUSG00000021609 10090 + 13:73536747-73578672 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000022100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000022100 0.008±0.00 0.055±0.04 0.014±0.00 1.000±0.42 0.031±0.01 0.038±0.01 0.014±0.00 0.037±0.03 0.326±0.13 0.058±0.02 0.055±0.05 0.037±0.03 0.021±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q6 CIL_0008Q6_0002 VISTA 13:72998274-73600313

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0005102 IEA receptor binding
GO:0005329 IMP dopamine transmembrane transporter activity
GO:0005330 IEA dopamine:sodium symporter activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006836 IEA neurotransmitter transport
GO:0007568 IEA aging
GO:0007595 IMP lactation
GO:0007608 IMP sensory perception of smell
GO:0007626 IGI locomotory behavior
GO:0008144 IEA drug binding
GO:0008504 ISO monoamine transmembrane transporter activity
GO:0010039 IEA response to iron ion
GO:0014070 IEA response to organic cyclic compound
GO:0015844 ISO monoamine transport
GO:0015872 IMP dopamine transport
GO:0021984 IMP adenohypophysis development
GO:0030424 IDA axon
GO:0032403 IEA protein complex binding
GO:0035094 IEA response to nicotine
GO:0035240 IDA dopamine binding
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0042053 IMP regulation of dopamine metabolic process
GO:0042220 IDA response to cocaine
GO:0042416 IMP dopamine biosynthetic process
GO:0042420 IMP dopamine catabolic process
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0045471 IEA response to ethanol
GO:0047485 IPI protein N-terminus binding
GO:0051591 IEA response to cAMP
GO:0060134 IMP prepulse inhibition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000129303 SLC6A3-201 protein_coding Danio_rerio 0 483
ENSDART00000027337 SLC6A3-202 protein_coding Danio_rerio 0 257
ENST00000270349 SLC6A3-001 protein_coding Homo_sapiens 0 2159
ENST00000513308 SLC6A3-002 protein_coding Homo_sapiens 0 953
ENST00000621716 SLC6A3-201 protein_coding Homo_sapiens 0 2159

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