C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023462 Mapk1-002 ENSMUSG00000063358 10090 + 16:16983382-17044749 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023462
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023462 9.591±2.22 11.667±0.10 26.922±3.85 33.271±13.60 10.507±4.50 22.180±5.90 11.243±0.98 8.171±1.91 16.427±6.15 12.343±4.27 12.402±0.79 18.128±5.06 27.646±5.68 4.466±1.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PT CIL_0008PT_0002 VISTA 16:16870677-17470725

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0001784 IMP phosphotyrosine binding
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IMP MAP kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005794 TAS Golgi apparatus
GO:0005829 IDA cytosol
GO:0005856 TAS cytoskeleton
GO:0005901 TAS caveola
GO:0005925 TAS focal adhesion
GO:0006351 NAS transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0009887 IDA organ morphogenesis
GO:0016301 IDA kinase activity
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0019858 IDA cytosine metabolic process
GO:0031143 IDA pseudopodium
GO:0031647 ISS regulation of protein stability
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032496 IDA response to lipopolysaccharide
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0033598 IDA mammary gland epithelial cell proliferation
GO:0043330 IDA response to exogenous dsRNA
GO:0045596 IGI negative regulation of cell differentiation
GO:0050852 IDA T cell receptor signaling pathway
GO:0050853 IDA B cell receptor signaling pathway
GO:0051090 NAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051493 TAS regulation of cytoskeleton organization
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0070849 ISS response to epidermal growth factor
GO:0072584 TAS caveolin-mediated endocytosis
GO:0072686 ISS mitotic spindle
GO:0090170 TAS regulation of Golgi inheritance
GO:0097011 IDA cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:2000641 TAS regulation of early endosome to late endosome transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000103746 mapk3-001 protein_coding Danio_rerio 0 612
ENST00000215832 MAPK1-001 protein_coding Homo_sapiens 0 1905
ENST00000398822 MAPK1-002 protein_coding Homo_sapiens 0 1605
ENST00000491588 MAPK1-003 processed_transcript Homo_sapiens 0 337
ENST00000544786 MAPK1-201 protein_coding Homo_sapiens 0 1031

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