C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome P450, family 1, subfamily b, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024894 Cyp1b1-201 ENSMUSG00000024087 10090 - 17:79706953-79715041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024894
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024894 2.109±0.98 19.666±1.77 9.634±1.18 1.475±1.01 13.028±5.38 0.253±0.12 1.510±0.41 9.661±3.19 0.119±0.05 4.248±0.56 0.141±0.20 70.761±24.49 0.293±0.41 2.312±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002IO CIL_0002IO_0002 CGP 17:79706953-79896123

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0002930 IMP trabecular meshwork development
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IMP mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0006725 IMP cellular aromatic compound metabolic process
GO:0006805 ISS xenobiotic metabolic process
GO:0006809 IMP nitric oxide biosynthetic process
GO:0007155 IMP cell adhesion
GO:0008202 ISS steroid metabolic process
GO:0008210 IDA estrogen metabolic process
GO:0008285 IMP negative regulation of cell proliferation
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009404 IMP toxin metabolic process
GO:0009636 IMP response to toxic substance
GO:0010575 IMP positive regulation vascular endothelial growth factor production
GO:0016020 IEA membrane
GO:0016712 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019369 IDA arachidonic acid metabolic process
GO:0020037 ISS heme binding
GO:0030199 IMP collagen fibril organization
GO:0030336 IMP negative regulation of cell migration
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0033629 IMP negative regulation of cell adhesion mediated by integrin
GO:0042572 IDA retinol metabolic process
GO:0042574 IDA retinal metabolic process
GO:0043065 IMP positive regulation of apoptotic process
GO:0043542 IMP endothelial cell migration
GO:0045766 IMP positive regulation of angiogenesis
GO:0046427 IMP positive regulation of JAK-STAT cascade
GO:0046466 IMP membrane lipid catabolic process
GO:0048514 IMP blood vessel morphogenesis
GO:0055114 IEA oxidation-reduction process
GO:0061298 IMP retina vasculature development in camera-type eye
GO:0061304 IMP retinal blood vessel morphogenesis
GO:0070301 IMP cellular response to hydrogen peroxide
GO:0070330 IEA aromatase activity
GO:0071407 ISO cellular response to organic cyclic compound
GO:0071603 IMP endothelial cell-cell adhesion
GO:1901313 IMP positive regulation of gene expression involved in extracellular matrix organization
GO:2000377 IMP regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000490576 CYP1B1-005 protein_coding Homo_sapiens 0 342
ENST00000610745 CYP1B1-001 protein_coding Homo_sapiens 0 1406
ENST00000614273 CYP1B1-003 protein_coding Homo_sapiens 0 1399

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