C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual specificity phosphatase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025025 Dusp1-001 ENSMUSG00000024190 10090 - 17:26505590-26508519 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025025
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025025 37.718±21.21 27.410±8.44 27.117±0.43 15.176±9.22 23.186±5.44 22.717±3.87 34.630±1.70 20.087±1.80 16.577±7.20 77.587±12.05 12.356±1.96 21.065±12.76 18.670±5.79 7.243±3.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KN CIL_0008KN_0002 VISTA 17:26208852-26810691
CIL_0000OU CIL_0000OU_0003 CGP 17:26414829-26508519

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0001706 IBA endoderm formation
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006470 IBA protein dephosphorylation
GO:0008138 IBA protein tyrosine/serine/threonine phosphatase activity
GO:0008330 IEA protein tyrosine/threonine phosphatase activity
GO:0009416 IEA response to light stimulus
GO:0010033 IEA response to organic substance
GO:0017017 ISS MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032355 IEA response to estradiol
GO:0032526 IEA response to retinoic acid
GO:0032870 IEA cellular response to hormone stimulus
GO:0033574 IEA response to testosterone
GO:0035335 ISS peptidyl-tyrosine dephosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0035970 ISS peptidyl-threonine dephosphorylation
GO:0042542 IEA response to hydrogen peroxide
GO:0042981 IBA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043409 ISS negative regulation of MAPK cascade
GO:0051384 IEA response to glucocorticoid
GO:0051447 ISS negative regulation of meiotic cell cycle
GO:0051591 IEA response to cAMP
GO:0051592 IEA response to calcium ion
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0071850 ISS mitotic cell cycle arrest
GO:0090266 ISS regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000279 IEA negative regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000239223 DUSP1-001 protein_coding Homo_sapiens 0 1921

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