C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: flap structure specific endonuclease 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025651 Fen1-004 ENSMUSG00000024742 10090 - 19:10199138-10204068 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENSMUST00000025651
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025651 4.045±1.64 4.908±0.97 2.052±0.24 4.328±0.00 3.736±0.04 3.294±0.90 22.941±14.61 2.970±0.04 1.702±0.10 6.108±2.20 10.515±5.25 7.393±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WT CIL_0007WT_0002 VISTA 19:10121785-10724671

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 IDA DNA binding
GO:0004527 IDA exonuclease activity
GO:0005634 TAS nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0005739 IEA mitochondrion
GO:0006260 IMP DNA replication
GO:0006281 IMP DNA repair
GO:0006284 IEA base-excision repair
GO:0008409 IEA 5'-3' exonuclease activity
GO:0017108 IEA 5'-flap endonuclease activity
GO:0030145 IDA manganese ion binding
GO:0043137 IEA DNA replication, removal of RNA primer
GO:0048256 IDA flap endonuclease activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000305885 FEN1-001 protein_coding Homo_sapiens 0 1506
ENST00000401028 FEN1P1-001 processed_pseudogene Homo_sapiens 0 1256
ENST00000497520 HFM1-004 processed_transcript Homo_sapiens 3e-29 132
ENST00000535307 FEN1-004 protein_coding Homo_sapiens 0 571
ENST00000535723 FEN1-003 protein_coding Homo_sapiens 0 689

Loading