C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired-like homeodomain transcription factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026259 Pitx3-001 ENSMUSG00000025229 10090 - 19:46135685-46148326 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026259
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026259 0.195±0.13 0.062±0.03 0.082±0.00 0.663±0.05 0.341±0.41 0.029±0.01 0.163±0.04 0.030±0.02 0.049±0.05 0.133±0.04 1.598±0.54 0.054±0.02 0.077±0.07 0.321±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WH CIL_0005WH_0002 CGP 19:46131897-46148326
CIL_0005WI CIL_0005WI_0002 CGP 19:46135685-46286510

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002088 IMP lens development in camera-type eye
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007626 IMP locomotory behavior
GO:0010468 IDA regulation of gene expression
GO:0030901 IMP midbrain development
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048666 IMP neuron development
GO:0070306 IMP lens fiber cell differentiation
GO:0071542 IMP dopaminergic neuron differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000062803 pitx1-201 protein_coding Danio_rerio 0 267
ENST00000370002 PITX3-001 protein_coding Homo_sapiens 0 1548
ENST00000539804 PITX3-201 protein_coding Homo_sapiens 0 1190

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