C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NIMA (never in mitosis gene a)-related expressed kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027931 Nek2-001 ENSMUSG00000026622 10090 + 1:191821444-191833050 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027931
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027931 0.987±0.51 0.627±0.13 0.428±0.02 2.747±0.97 0.399±0.17 2.700±0.87 0.163±0.05 0.302±0.11 6.173±6.82 1.132±0.53 0.090±0.04 2.939±1.12 9.846±6.40 48.421±21.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041V CIL_00041V_0002 CGP 1:191717834-191833050
CIL_00042A CIL_00042A_0002 CGP 1:191821444-191913247

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000070 IMP mitotic sister chromatid segregation
GO:0000776 IEA kinetochore
GO:0000794 IDA condensed nuclear chromosome
GO:0000922 IDA spindle pole
GO:0001824 IMP blastocyst development
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0006468 IDA protein phosphorylation
GO:0007059 IMP chromosome segregation
GO:0019903 IEA protein phosphatase binding
GO:0030496 IDA midbody
GO:0043234 IEA protein complex
GO:0043392 IDA negative regulation of DNA binding
GO:0045171 IEA intercellular bridge
GO:0046777 ISS protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0051299 IEA centrosome separation
GO:0051321 IEA meiotic cell cycle
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0090307 IMP spindle assembly involved in mitosis
GO:1903126 IEA negative regulation of centriole-centriole cohesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000425793 NEK2P4-001 processed_pseudogene Homo_sapiens 0 963
ENST00000438441 NEK2P2-001 processed_pseudogene Homo_sapiens 0 968
ENST00000547023 RP11-244H18.4-001 processed_pseudogene Homo_sapiens 0 952
ENST00000547616 RP11-536C10.10-001 transcribed_processed_pseudogene Homo_sapiens 0 955
ENST00000613011 RP11-536C10.26-001 processed_pseudogene Homo_sapiens 0 983

Loading