C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SH2B adaptor protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032978 Sh2b1-201 ENSMUSG00000030733 10090 - 7:126466994-126475130 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032978 9.366±0.36 6.515±1.46 6.688±2.07 4.596±0.00 3.961±0.66 4.510±1.49 4.546±1.71 2.538±0.00 2.598±1.51 8.766±0.65 7.987±3.23 9.235±5.13 9.168±4.56 2.250±0.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 TAS ruffle
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006928 IDA cellular component movement
GO:0016020 IEA membrane
GO:0030032 IDA lamellipodium assembly
GO:0035556 IEA intracellular signal transduction
GO:0045840 IDA positive regulation of mitosis
GO:2000278 IMP regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000322610 SH2B1-001 protein_coding Homo_sapiens 0 2213
ENST00000337120 SH2B1-002 protein_coding Homo_sapiens 0 2220
ENST00000359285 SH2B1-003 protein_coding Homo_sapiens 0 3116
ENST00000395532 SH2B1-006 protein_coding Homo_sapiens 0 2217
ENST00000536178 SH2B2-001 protein_coding Homo_sapiens 6e-23 113
ENST00000538342 SH2B1-005 protein_coding Homo_sapiens 0 1114
ENST00000545570 SH2B1-004 protein_coding Homo_sapiens 0 1652
ENST00000561629 SH2B1-011 protein_coding Homo_sapiens 0 213
ENST00000563591 SH2B1-008 protein_coding Homo_sapiens 0 257
ENST00000563674 SH2B1-013 processed_transcript Homo_sapiens 0 534
ENST00000566176 SH2B1-010 protein_coding Homo_sapiens 0 588
ENST00000566209 SH2B1-007 protein_coding Homo_sapiens 0 252
ENST00000568868 SH2B1-014 protein_coding Homo_sapiens 0 429
ENST00000569651 SH2B1-015 protein_coding Homo_sapiens 0 516
ENST00000618521 SH2B1-201 protein_coding Homo_sapiens 0 2217

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