C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SH2B adaptor protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000536178 SH2B2-001 ENSG00000160999 9606 + 7:102285155-102321711 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000536178
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000536178 1.539±0.00 6.774±0.00 0.047±0.00 0.691±0.27 2.653±0.00 0.213±0.00 1.611±0.00 0.326±0.00 3.231±2.75 2.051±0.65 1.243±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FZ CIL_0002FZ_0002 CGP 7:101815904-102321711

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0001726 IEA ruffle
GO:0001922 IEA B-1 B cell homeostasis
GO:0004871 IEA signal transducer activity
GO:0005068 IEA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005070 IDA SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IEA actin filament
GO:0005886 IDA plasma membrane
GO:0007165 TAS signal transduction
GO:0007399 IEA nervous system development
GO:0007596 TAS blood coagulation
GO:0008269 IDA JAK pathway signal transduction adaptor activity
GO:0008286 ISS insulin receptor signaling pathway
GO:0009967 IEA positive regulation of signal transduction
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019222 IEA regulation of metabolic process
GO:0030036 IEA actin cytoskeleton organization
GO:0035556 IDA:IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0046425 IDA regulation of JAK-STAT cascade
GO:0046578 IEA regulation of Ras protein signal transduction
GO:0050776 IEA regulation of immune response
GO:0050851 IEA antigen receptor-mediated signaling pathway
GO:0050873 IEA brown fat cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005188 Sh2b2-201 protein_coding Mus_musculus 0 1411
ENSMUST00000032978 Sh2b1-201 protein_coding Mus_musculus 6e-23 113

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