C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP dependent regulatory, type II beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000036497 Prkar2b-001 ENSMUSG00000002997 10090 - 12:31958476-32061296 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036497
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036497 54.378±28.01 138.383±68.29 4.225±0.64 24.996±16.13 54.938±21.45 3.211±1.22 4.096±1.93 5.961±1.30 16.940±18.61 7.275±1.52 0.487±0.35 77.091±52.05 2.632±2.07 1.187±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055N CIL_00055N_0002 CGP 12:31926254-32061296

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004862 IEA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005886 IEA plasma membrane
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006631 IMP fatty acid metabolic process
GO:0007612 IMP learning
GO:0008603 IDA cAMP-dependent protein kinase regulator activity
GO:0019901 IPI protein kinase binding
GO:0030552 IEA cAMP binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0034236 IEA protein kinase A catalytic subunit binding
GO:0043197 IDA dendritic spine
GO:0043198 IDA dendritic shaft
GO:0070062 IEA extracellular vesicular exosome
GO:0097546 IDA ciliary base
GO:2000480 IEA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265563 PRKAR2A-001 protein_coding Homo_sapiens 0 339
ENST00000265717 PRKAR2B-001 protein_coding Homo_sapiens 0 2224
ENST00000296446 PRKAR2A-003 protein_coding Homo_sapiens 2e-35 156
ENST00000393613 PRKAR2B-003 processed_transcript Homo_sapiens 0 383
ENST00000454963 PRKAR2A-002 protein_coding Homo_sapiens 0 339
ENST00000457914 PRKAR2A-004 protein_coding Homo_sapiens 2e-36 156
ENST00000488792 PRKAR2B-004 processed_transcript Homo_sapiens 0 573

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