C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP-dependent, regulatory, type II, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265563 PRKAR2A-001 ENSG00000114302 9606 - 3:48746579-48847846 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265563
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265563 11.014±0.00 5.061±0.00 1.586±0.00 3.585±2.15 7.025±4.01 2.423±0.56 6.790±4.89 3.735±1.12 4.011±0.00 2.334±0.03 15.622±12.32 6.297±3.31 4.975±2.29 7.719±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003FN CIL_0003FN_0002 CGP 3:48744597-48898993

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IDA:IEA cAMP-dependent protein kinase regulator activity
GO:0016020 IDA membrane
GO:0030552 IEA cAMP binding
GO:0031588 IDA AMP-activated protein kinase complex
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0035556 TAS intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035220 Prkar2a-201 protein_coding Mus_musculus 0 1842
ENSMUST00000146865 Prkar2b-003 protein_coding Mus_musculus 0 339
ENSMUST00000036497 Prkar2b-001 protein_coding Mus_musculus 0 339
ENSMUST00000003079 Prkar2b-002 protein_coding Mus_musculus 0 339
ENSMUST00000179332 5730455P16Rik-201 protein_coding Mus_musculus 0.000000001 71
ENSMUST00000103225 5730455P16Rik-001 protein_coding Mus_musculus 0.000000001 71

Loading