C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037607 Map3k7-001 ENSMUSG00000028284 10090 + 4:31964097-32023467 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000037607
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000037607 6.660±0.92 8.035±2.62 5.546±0.67 2.748±1.30 6.457±1.47 10.522±0.64 5.577±1.09 8.940±1.24 7.014±1.69 6.230±1.19 9.119±3.27 6.561±3.94 3.596±1.58

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0000187 IEA activation of MAPK activity
GO:0000287 IEA magnesium ion binding
GO:0001525 IMP angiogenesis
GO:0001841 IMP neural tube formation
GO:0002726 IEA positive regulation of T cell cytokine production
GO:0004708 IDA MAP kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005671 IEA Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737 IEA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0007252 IGI I-kappaB phosphorylation
GO:0007254 IEA JNK cascade
GO:0008385 IEA IkappaB kinase complex
GO:0032743 IEA positive regulation of interleukin-2 production
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0043966 IEA histone H3 acetylation
GO:0046330 IGI positive regulation of JNK cascade
GO:0051403 IEA stress-activated MAPK cascade
GO:0097110 ISO scaffold protein binding
GO:1902443 IGI negative regulation of ripoptosome assembly involved in necroptotic process
GO:2000377 IMP regulation of reactive oxygen species metabolic process
GO:2001234 IGI negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369320 MAP3K7-006 protein_coding Homo_sapiens 0 1011
ENST00000369325 MAP3K7-003 protein_coding Homo_sapiens 0 2089
ENST00000369327 MAP3K7-004 protein_coding Homo_sapiens 0 1637
ENST00000369329 MAP3K7-002 protein_coding Homo_sapiens 0 2808
ENST00000369332 MAP3K7-001 protein_coding Homo_sapiens 0 1663
ENST00000479630 MAP3K7-005 processed_transcript Homo_sapiens 0 1009

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