C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: low density lipoprotein receptor adaptor protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037828 Ldlrap1-001 ENSMUSG00000037295 10090 - 4:134744735-134768024 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037828 6.786±0.62 13.868±1.91 8.155±0.48 0.680±0.02 7.543±2.98 4.730±1.02 3.583±0.78 7.814±1.05 6.660±2.13 12.709±0.36 1.204±0.26 6.995±1.94 17.076±12.85 0.707±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HZ CIL_0008HZ_0002 VISTA 4:134170100-134773977

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001540 IPI beta-amyloid binding
GO:0001784 ISS phosphotyrosine binding
GO:0005102 ISA receptor binding
GO:0005515 IPI protein binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005769 IDA early endosome
GO:0005829 ISS cytosol
GO:0005883 IDA neurofilament
GO:0006898 IEA receptor-mediated endocytosis
GO:0008203 IEA cholesterol metabolic process
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0009925 ISS basal plasma membrane
GO:0009967 IEA positive regulation of signal transduction
GO:0030121 ISS AP-1 adaptor complex
GO:0030122 ISS AP-2 adaptor complex
GO:0030159 IEA receptor signaling complex scaffold activity
GO:0030276 ISS clathrin binding
GO:0030424 IEA axon
GO:0031623 IEA receptor internalization
GO:0035591 IEA signaling adaptor activity
GO:0035612 IEA AP-2 adaptor complex binding
GO:0035615 IEA clathrin adaptor activity
GO:0042632 IMP cholesterol homeostasis
GO:0042982 IEA amyloid precursor protein metabolic process
GO:0043393 IEA regulation of protein binding
GO:0048260 ISS positive regulation of receptor-mediated endocytosis
GO:0050750 IEA low-density lipoprotein particle receptor binding
GO:0055037 IEA recycling endosome
GO:0090003 IEA regulation of establishment of protein localization to plasma membrane
GO:0090118 IEA receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000374338 LDLRAP1-001 protein_coding Homo_sapiens 0 1061
ENST00000462394 LDLRAP1-007 processed_transcript Homo_sapiens 0 276
ENST00000488127 LDLRAP1-002 processed_transcript Homo_sapiens 0 693

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