C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, polypeptide 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000043599 Rps6ka5-201 ENSMUSG00000021180 10090 - 12:100549778-100725028 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043599
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043599 1.398±0.00 0.472±0.19 0.407±0.00 1.085±0.19 0.540±0.09 1.306±0.04 0.529±0.24 0.273±0.15 1.294±0.55 0.309±0.03 1.146±0.43 0.389±0.11 0.830±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CD CIL_0005CD_0002 CGP 12:100300771-100725028
CIL_0005CC CIL_0005CC_0002 CGP 12:100549778-100896981

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0033129 IEA positive regulation of histone phosphorylation
GO:0035066 IEA positive regulation of histone acetylation
GO:0035556 IDA intracellular signal transduction
GO:0043987 ISS histone H3-S10 phosphorylation
GO:0043988 ISS histone H3-S28 phosphorylation
GO:0043990 ISS histone H2A-S1 phosphorylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070498 IEA interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261991 RPS6KA5-201 protein_coding Homo_sapiens 0 2015
ENST00000418736 RPS6KA5-003 protein_coding Homo_sapiens 0 2015
ENST00000536315 RPS6KA5-004 protein_coding Homo_sapiens 0 1845
ENST00000554206 RPS6KA5-002 nonsense_mediated_decay Homo_sapiens 0 881
ENST00000556178 RPS6KA5-005 nonsense_mediated_decay Homo_sapiens 0 1295
ENST00000556594 RPS6KA5-006 nonsense_mediated_decay Homo_sapiens 0 270
ENST00000614987 RPS6KA5-001 protein_coding Homo_sapiens 0 2015

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