C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, 90kDa, polypeptide 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000614987 RPS6KA5-001 ENSG00000100784 9606 - 14:90847862-91060608 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainLiverLungOvaryPlacentaENST00000614987
Transcript ID Adipose Adrenal Bladder Brain Liver Lung Ovary Placenta
ENST00000614987 0.230±0.00 0.434±0.00 0.225±0.00 0.869±0.14 0.080±0.00 0.559±0.00 0.461±0.00 0.806±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CD CIL_0005CD_0001 CGP 14:90524564-91060636
CIL_0005CC CIL_0005CC_0001 CGP 14:90847862-91225632

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001818 TAS negative regulation of cytokine production
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 IMP:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IMP nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005840 IEA ribosome
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006468 IDA:IEA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016572 TAS histone phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0032793 TAS positive regulation of CREB transcription factor activity
GO:0033129 IMP positive regulation of histone phosphorylation
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035066 IMP positive regulation of histone acetylation
GO:0035556 IDA:IEA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043987 IMP histone H3-S10 phosphorylation
GO:0043988 IMP histone H3-S28 phosphorylation
GO:0043990 IDA histone H2A-S1 phosphorylation
GO:0045087 TAS innate immune response
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0070498 IMP interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043599 Rps6ka5-201 protein_coding Mus_musculus 0 2015
ENSMUST00000078259 Nsl1-001 protein_coding Mus_musculus 0.000000000008 81
ENSMUST00000091299 Cdk7-201 protein_coding Mus_musculus 0.00004 58
ENSMUST00000157025 Ctr9-003 retained_intron Mus_musculus 0.002 53
ENSMUST00000152019 Ctr9-002 retained_intron Mus_musculus 0.002 53

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