C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitochondrial ubiquitin ligase activator of NFKB 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000044058 Mul1-001 ENSMUSG00000041241 10090 + 4:138434671-138442265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000044058
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000044058 3.340±0.06 4.332±0.00 1.186±0.00 1.120±0.22 2.012±0.40 8.703±3.08 4.263±1.58 4.030±0.44 1.977±1.55 2.759±0.90 3.524±1.36 1.890±1.32 5.682±2.75

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000266 ISS mitochondrial fission
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0004871 ISS signal transducer activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005777 ISS peroxisome
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257 ISS activation of JUN kinase activity
GO:0008270 IEA zinc ion binding
GO:0010637 IEA negative regulation of mitochondrial fusion
GO:0016020 IEA membrane
GO:0016567 ISS protein ubiquitination
GO:0016925 IEA protein sumoylation
GO:0019789 IEA SUMO ligase activity
GO:0030308 ISS negative regulation of cell growth
GO:0031307 ISS integral component of mitochondrial outer membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0033235 IEA positive regulation of protein sumoylation
GO:0042802 ISS identical protein binding
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045824 ISS negative regulation of innate immune response
GO:0050689 ISS negative regulation of defense response to virus by host
GO:0050821 IEA protein stabilization
GO:0051646 ISS mitochondrion localization
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060339 ISS negative regulation of type I interferon-mediated signaling pathway
GO:0071360 ISS cellular response to exogenous dsRNA
GO:0071650 ISS negative regulation of chemokine (C-C motif) ligand 5 production
GO:0090141 IEA positive regulation of mitochondrial fission
GO:1901028 ISS regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264198 MUL1-001 protein_coding Homo_sapiens 0 1192

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