C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: cardiotrophin-like cytokine factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000046506 Clcf1-001 ENSMUSG00000040663 10090 + 19:4214238-4223490 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonKidneyLiverMuscleOvaryPlacentaENSMUST00000046506
Transcript ID Adipose Adrenal Bladder Breast Colon Kidney Liver Muscle Ovary Placenta
ENSMUST00000046506 2.256±1.21 0.958±0.16 1.721±0.00 10.895±0.59 0.639±0.08 0.851±0.00 0.426±0.04 0.140±0.06 2.689±0.00 0.282±0.12

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002639 IDA positive regulation of immunoglobulin production
GO:0002830 NAS positive regulation of type 2 immune response
GO:0005102 ISS receptor binding
GO:0005125 IDA cytokine activity
GO:0005127 ISS ciliary neurotrophic factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 ISS extracellular region
GO:0005622 TAS intracellular
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007259 IDA JAK-STAT cascade
GO:0008284 ISS positive regulation of cell proliferation
GO:0030183 IDA B cell differentiation
GO:0030890 IDA positive regulation of B cell proliferation
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0046982 ISS protein heterodimerization activity
GO:0048295 IDA positive regulation of isotype switching to IgE isotypes
GO:0048711 IDA positive regulation of astrocyte differentiation
GO:0050727 NAS regulation of inflammatory response
GO:0051466 TAS positive regulation of corticotropin-releasing hormone secretion
GO:0051896 TAS regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0070372 TAS regulation of ERK1 and ERK2 cascade
GO:0097058 IEA CRLF-CLCF1 complex
GO:0097059 IEA CNTFR-CLCF1 complex
GO:2000672 NAS negative regulation of motor neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000312438 CLCF1-002 protein_coding Homo_sapiens 0 1234
ENST00000533438 CLCF1-001 protein_coding Homo_sapiens 0 928
ENST00000543494 AP003419.11-001 protein_coding Homo_sapiens 1e-20 104

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