C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual specificity phosphatase 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000048655 Dusp10-001 ENSMUSG00000039384 10090 + 1:184034381-184075636 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048655
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048655 6.046±1.49 2.827±0.61 4.163±0.77 1.635±0.87 8.590±4.52 3.796±0.68 3.283±0.99 1.421±0.31 2.245±0.30 3.217±0.38 10.329±4.22 3.961±2.02 1.333±0.75 6.633±3.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C7 CIL_0009C7_0002 VISTA 1:183741270-184342762
CIL_0007Q6 CIL_0007Q6_0002 VISTA 1:183741272-184341272

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0002819 IMP regulation of adaptive immune response
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0006470 IBA:ISS protein dephosphorylation
GO:0008138 IBA protein tyrosine/serine/threonine phosphatase activity
GO:0010033 IEA response to organic substance
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032496 IMP response to lipopolysaccharide
GO:0032873 IMP negative regulation of stress-activated MAPK cascade
GO:0033549 ISS MAP kinase phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043508 IMP negative regulation of JUN kinase activity
GO:0044387 IDA negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045088 IMP regulation of innate immune response
GO:0046329 IMP negative regulation of JNK cascade
GO:0048709 IMP oligodendrocyte differentiation
GO:0048715 IEA negative regulation of oligodendrocyte differentiation
GO:0060266 IMP negative regulation of respiratory burst involved in inflammatory response
GO:0090335 IDA regulation of brown fat cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000366899 DUSP10-001 protein_coding Homo_sapiens 0 2285
ENST00000468085 DUSP10-003 nonsense_mediated_decay Homo_sapiens 0 918
ENST00000477026 DUSP10-002 nonsense_mediated_decay Homo_sapiens 0 917
ENST00000494642 DUSP10-004 nonsense_mediated_decay Homo_sapiens 0 869

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