C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mucosa associated lymphoid tissue lymphoma translocation gene 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049248 Malt1-001 ENSMUSG00000032688 10090 + 18:65430963-65478823 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049248
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049248 4.257±2.24 7.280±1.34 3.488±1.34 0.993±0.40 9.793±3.52 5.342±0.38 1.489±0.58 2.610±0.99 1.949±1.03 4.698±1.78 0.396±0.28 5.167±1.57 1.906±0.52 1.853±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00086L CIL_00086L_0002 VISTA 18:65229356-65832579
CIL_0006OD CIL_0006OD_0002 CGP 18:65265529-65478823
CIL_0006O5 CIL_0006O5_0002 CGP 18:65430963-65689443

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001923 IMP B-1 B cell differentiation
GO:0002020 IPI protease binding
GO:0002237 IEP response to molecule of bacterial origin
GO:0002726 IEA positive regulation of T cell cytokine production
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006915 RCA apoptotic process
GO:0007249 RCA I-kappaB kinase/NF-kappaB signaling
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0008233 IEA peptidase activity
GO:0009620 IMP response to fungus
GO:0016567 IEA protein ubiquitination
GO:0019209 IEA kinase activator activity
GO:0032743 IEA positive regulation of interleukin-2 production
GO:0042098 IMP T cell proliferation
GO:0042113 IMP B cell activation
GO:0042981 ISA regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IEA protein complex
GO:0043621 IEA protein self-association
GO:0045087 IEP innate immune response
GO:0050852 TAS T cell receptor signaling pathway
GO:0050856 IMP regulation of T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051168 IEA nuclear export
GO:0051259 IEA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000345724 MALT1-002 protein_coding Homo_sapiens 0 2627
ENST00000348428 MALT1-001 protein_coding Homo_sapiens 0 1676
ENST00000587438 MALT1-005 retained_intron Homo_sapiens 0 514
ENST00000589873 MALT1-003 retained_intron Homo_sapiens 0 1031
ENST00000591792 MALT1-004 protein_coding Homo_sapiens 0 497

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