C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: intersectin 1 (SH3 domain protein 1A)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000056482 Itsn1-003 ENSMUSG00000022957 10090 + 16:91729371-91871655 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056482
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056482 9.436±2.42 13.585±2.55 13.263±5.52 6.378±0.84 2.272±0.60 6.196±1.54 2.373±0.40 6.864±5.84 6.391±3.63 13.934±0.94 12.991±8.85 8.934±3.36 2.104±0.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00078C CIL_00078C_0002 CGP 16:91677268-91931687
CIL_0005TE CIL_0005TE_0002 CGP 16:91684398-91931687
CIL_00078A CIL_00078A_0002 CGP 16:91689322-91920597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0006897 IEA endocytosis
GO:0007264 IDA small GTPase mediated signal transduction
GO:0019209 IDA kinase activator activity
GO:0030027 IDA lamellipodium
GO:0030054 IEA cell junction
GO:0030139 IDA endocytic vesicle
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0042327 IDA positive regulation of phosphorylation
GO:0043005 IEA neuron projection
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0051897 IDA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000379960 ITSN1-201 protein_coding Homo_sapiens 0 2726
ENST00000381283 ITSN1-036 protein_coding Homo_sapiens 0 804
ENST00000381285 ITSN1-202 protein_coding Homo_sapiens 0 2300
ENST00000381291 ITSN1-002 protein_coding Homo_sapiens 0 5254
ENST00000381318 ITSN1-001 protein_coding Homo_sapiens 0 4263
ENST00000399338 ITSN1-203 protein_coding Homo_sapiens 0 2894
ENST00000399349 ITSN1-003 protein_coding Homo_sapiens 0 3474
ENST00000399352 ITSN1-024 protein_coding Homo_sapiens 0 5325
ENST00000399353 ITSN1-025 protein_coding Homo_sapiens 0 3591
ENST00000399355 ITSN1-037 protein_coding Homo_sapiens 0 3406
ENST00000399367 ITSN1-023 protein_coding Homo_sapiens 0 4331
ENST00000428240 ITSN1-016 processed_transcript Homo_sapiens 9e-32 139
ENST00000437126 ITSN1-006 nonsense_mediated_decay Homo_sapiens 0 237
ENST00000437442 ITSN1-204 protein_coding Homo_sapiens 0 1467
ENST00000444491 ITSN1-033 protein_coding Homo_sapiens 0 486
ENST00000456489 ITSN1-017 protein_coding Homo_sapiens 0 230
ENST00000462212 ITSN1-013 retained_intron Homo_sapiens 0 592
ENST00000470742 ITSN1-034 processed_transcript Homo_sapiens 0 357
ENST00000472548 ITSN1-008 processed_transcript Homo_sapiens 0 590
ENST00000475422 ITSN1-011 retained_intron Homo_sapiens 1e-31 141
ENST00000479424 ITSN1-010 processed_transcript Homo_sapiens 0 590
ENST00000487427 ITSN1-007 retained_intron Homo_sapiens 0 743
ENST00000488166 ITSN1-019 processed_transcript Homo_sapiens 0 577
ENST00000489261 ITSN1-012 retained_intron Homo_sapiens 0 497
ENST00000495656 ITSN1-009 processed_transcript Homo_sapiens 0 496
ENST00000504159 RP11-215G15.4-001 processed_pseudogene Homo_sapiens 0 767

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