C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X-C motif) receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000056614 Cxcr3-001 ENSMUSG00000050232 10090 - X:101731535-101734269 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056614
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056614 2.136±0.65 0.974±0.19 0.849±0.31 0.034±0.00 10.628±2.41 1.636±0.31 0.232±0.07 1.383±0.43 0.651±0.41 2.212±0.47 0.104±0.06 1.894±0.80 0.085±0.09 0.062±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065Y CIL_00065Y_0002 CGP X:101731535-101798642

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0002685 IEA regulation of leukocyte migration
GO:0004872 ISS receptor activity
GO:0004950 IEA chemokine receptor activity
GO:0005886 ISS plasma membrane
GO:0006954 IEA inflammatory response
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008284 ISS positive regulation of cell proliferation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010818 IEA T cell chemotaxis
GO:0016021 IEA integral component of membrane
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0016525 IEA negative regulation of angiogenesis
GO:0019722 IEA calcium-mediated signaling
GO:0019956 IEA chemokine binding
GO:0019958 ISS C-X-C chemokine binding
GO:0030816 IEA positive regulation of cAMP metabolic process
GO:0043950 IEA positive regulation of cAMP-mediated signaling
GO:0045766 ISS positive regulation of angiogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050921 ISS positive regulation of chemotaxis
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0071954 ISS chemokine (C-C motif) ligand 11 production
GO:1900118 ISS negative regulation of execution phase of apoptosis
GO:1900119 IEA positive regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000373691 CXCR3-001 protein_coding Homo_sapiens 0 1005
ENST00000373693 CXCR3-002 protein_coding Homo_sapiens 0 1051

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