C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: toll-like receptor 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062315 Tlr6-201 ENSMUSG00000051498 10090 - 5:64953106-64960048 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062315
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062315 0.505±0.24 0.609±0.16 0.155±0.05 0.045±0.03 0.878±0.24 0.833±0.45 0.151±0.03 0.198±0.04 0.139±0.04 0.700±0.27 0.108±0.03 0.421±0.21 0.218±0.16 0.052±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A6 CIL_0007A6_0002 CGP 5:64924811-64960048
CIL_0007A8 CIL_0007A8_0002 CGP 5:64953106-65041874

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004888 IEA transmembrane signaling receptor activity
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034150 IEA toll-like receptor 6 signaling pathway
GO:0035355 IDA Toll-like receptor 2-Toll-like receptor 6 protein complex
GO:0042088 IEA:IC T-helper 1 type immune response
GO:0042496 IEA detection of diacyl bacterial lipopeptide
GO:0042498 IDA diacyl lipopeptide binding
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045084 NAS positive regulation of interleukin-12 biosynthetic process
GO:0045087 IEA innate immune response
GO:0045410 IEA:ISS positive regulation of interleukin-6 biosynthetic process
GO:0046982 IPI protein heterodimerization activity
GO:0050707 IEA regulation of cytokine secretion
GO:0071723 IMP lipopeptide binding
GO:0071726 IEA cellular response to diacyl bacterial lipopeptide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000381950 TLR6-001 protein_coding Homo_sapiens 0 1509
ENST00000436693 TLR6-201 protein_coding Homo_sapiens 0 1509

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