C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: toll-like receptor 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381950 TLR6-001 ENSG00000174130 9606 - 4:38826602-38829539 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastOvaryENST00000381950
Transcript ID Breast Ovary
ENST00000381950 0.756±0.00 0.682±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A6 CIL_0007A6_0001 CGP 4:38790677-38856817
CIL_0007A8 CIL_0007A8_0001 CGP 4:38823715-38945739

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS:IEA toll-like receptor signaling pathway
GO:0002755 IEA:TAS MyD88-dependent toll-like receptor signaling pathway
GO:0004872 TAS receptor activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS:IEA immune response
GO:0007165 TAS:IEA signal transduction
GO:0007250 NAS activation of NF-kappaB-inducing kinase activity
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034150 IEA toll-like receptor 6 signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042088 IEA:IC T-helper 1 type immune response
GO:0042496 IEA:IDA detection of diacyl bacterial lipopeptide
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 IDA positive regulation of JUN kinase activity
GO:0045087 TAS innate immune response
GO:0045410 IEA:ISS positive regulation of interleukin-6 biosynthetic process
GO:0050707 IEA regulation of cytokine secretion
GO:0071723 ISS lipopeptide binding
GO:0071726 IDA cellular response to diacyl bacterial lipopeptide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062315 Tlr6-201 protein_coding Mus_musculus 0 1509
ENSMUST00000059349 Tlr1-201 protein_coding Mus_musculus 0 863

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