C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ghrelin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064993 Ghrl-201 ENSMUSG00000064177 10090 - 6:113716119-113719880 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonOvaryTestisENSMUST00000064993
Transcript ID Adrenal Colon Ovary Testis
ENSMUST00000064993 0.379±0.08 0.527±0.22 0.914±0.46 5.732±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064Z CIL_00064Z_0002 CGP 6:113697050-113719880
CIL_00064V CIL_00064V_0002 CGP 6:113716119-113740743

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0001664 IEA G-protein coupled receptor binding
GO:0001696 IEA gastric acid secretion
GO:0001937 ISS negative regulation of endothelial cell proliferation
GO:0005179 ISS hormone activity
GO:0005576 ISS extracellular region
GO:0005615 ISS extracellular space
GO:0005737 IDA cytoplasm
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0008154 ISS actin polymerization or depolymerization
GO:0008343 IDA adult feeding behavior
GO:0009725 ISS response to hormone
GO:0016358 ISS dendrite development
GO:0016608 ISS growth hormone-releasing hormone activity
GO:0030296 ISS protein tyrosine kinase activator activity
GO:0030424 ISS axon
GO:0031768 ISS ghrelin receptor binding
GO:0032024 ISS positive regulation of insulin secretion
GO:0032095 ISS regulation of response to food
GO:0032097 ISS positive regulation of response to food
GO:0032100 IDA positive regulation of appetite
GO:0032691 ISS negative regulation of interleukin-1 beta production
GO:0040013 IMP negative regulation of locomotion
GO:0042127 ISS regulation of cell proliferation
GO:0042322 IEA negative regulation of circadian sleep/wake cycle, REM sleep
GO:0042536 ISS negative regulation of tumor necrosis factor biosynthetic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043627 ISS response to estrogen
GO:0045409 ISS negative regulation of interleukin-6 biosynthetic process
GO:0046010 IEA positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676 ISS negative regulation of insulin secretion
GO:0046697 ISS decidualization
GO:0050728 ISS negative regulation of inflammatory response
GO:0051461 IEA positive regulation of corticotropin secretion
GO:0051464 IEA positive regulation of cortisol secretion
GO:0051965 ISS positive regulation of synapse assembly
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060124 IEA positive regulation of growth hormone secretion
GO:0061098 IEA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000287656 GHRL-008 protein_coding Homo_sapiens 0 351
ENST00000335542 GHRL-001 protein_coding Homo_sapiens 0 372
ENST00000422159 GHRL-002 protein_coding Homo_sapiens 0 219
ENST00000425479 GHRL-014 protein_coding Homo_sapiens 1e-21 106
ENST00000429122 GHRL-005 protein_coding Homo_sapiens 0 372
ENST00000430179 GHRL-006 protein_coding Homo_sapiens 0 351
ENST00000457360 GHRL-009 protein_coding Homo_sapiens 0 372
ENST00000481287 GHRL-015 retained_intron Homo_sapiens 0 372

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