C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho-associated coiled-coil containing protein kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000067947 Rock1-201 ENSMUSG00000024290 10090 - 18:10064401-10181792 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067947
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067947 3.834±1.07 8.485±1.28 4.785±1.30 2.920±1.30 2.731±0.68 4.287±2.23 3.041±0.83 2.952±0.67 2.256±0.75 5.617±1.53 1.211±0.24 6.401±7.16 11.488±10.21 3.118±2.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00015E CIL_00015E_0002 CGP 18:9995432-10181792
CIL_0005O1 CIL_0005O1_0002 CGP 18:10064401-10562934

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0003383 IGI apical constriction
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005794 IEA Golgi apparatus
GO:0005856 IDA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007266 ISO Rho protein signal transduction
GO:0016525 IEA negative regulation of angiogenesis
GO:0017048 IEA Rho GTPase binding
GO:0022614 IEA membrane to membrane docking
GO:0030027 IDA lamellipodium
GO:0030036 IGI actin cytoskeleton organization
GO:0032060 IMP bleb assembly
GO:0032970 IGI regulation of actin filament-based process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045616 IEA regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0050900 IEA leukocyte migration
GO:0050901 IEA leukocyte tethering or rolling
GO:0051451 IMP myoblast migration
GO:0051894 IMP positive regulation of focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000399799 ROCK1-001 protein_coding Homo_sapiens 0 6431
ENST00000573767 ROCK1P1-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 737
ENST00000576266 ROCK1P1-002 processed_transcript Homo_sapiens 0 510
ENST00000578051 ROCK1-003 protein_coding Homo_sapiens 0 411
ENST00000582445 ROCK1-006 retained_intron Homo_sapiens 0 453
ENST00000583556 ROCK1-005 retained_intron Homo_sapiens 0 422
ENST00000584687 ROCK1-002 retained_intron Homo_sapiens 0 377
ENST00000608049 ROCK1P1-003 processed_transcript Homo_sapiens 0 1498

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