C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080933 Map3k7-002 ENSMUSG00000028284 10090 + 4:31964120-32023467 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080933
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080933 5.623±2.76 5.005±2.13 7.975±1.19 8.901±3.02 5.048±0.91 2.287±0.24 3.016±0.35 1.722±0.15 2.042±0.75 5.477±0.40 10.998±0.27 7.077±2.40 4.019±0.80 0.966±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0000187 IDA activation of MAPK activity
GO:0000287 IEA magnesium ion binding
GO:0001525 IMP angiogenesis
GO:0001841 IMP neural tube formation
GO:0004708 IDA MAP kinase kinase activity
GO:0004709 ISS MAP kinase kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006950 IEA response to stress
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007252 ISS I-kappaB phosphorylation
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 ISS positive regulation of JUN kinase activity
GO:0046330 IGI positive regulation of JNK cascade
GO:0060546 IMP negative regulation of necroptotic process
GO:0097110 ISO scaffold protein binding
GO:1902443 IGI negative regulation of ripoptosome assembly involved in necroptotic process
GO:2000377 IMP regulation of reactive oxygen species metabolic process
GO:2000378 IMP negative regulation of reactive oxygen species metabolic process
GO:2001234 IGI negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369320 MAP3K7-006 protein_coding Homo_sapiens 0 1452
ENST00000369325 MAP3K7-003 protein_coding Homo_sapiens 0 1626
ENST00000369327 MAP3K7-004 protein_coding Homo_sapiens 0 1956
ENST00000369329 MAP3K7-002 protein_coding Homo_sapiens 0 1663
ENST00000369332 MAP3K7-001 protein_coding Homo_sapiens 0 2663
ENST00000479630 MAP3K7-005 processed_transcript Homo_sapiens 0 1009

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