C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutathione peroxidase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000082429 Gpx1-201 ENSMUSG00000063856 10090 + 9:108339080-108340338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082429
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082429 485.222±143.98 574.979±83.16 202.188±7.13 100.633±14.03 422.898±148.06 441.392±38.07 84.497±28.15 1891.683±110.54 2511.224±680.81 355.749±50.70 42.783±5.74 361.124±77.56 407.076±143.75 26.123±3.46

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000302 IMP response to reactive oxygen species
GO:0001659 IGI temperature homeostasis
GO:0001885 IMP endothelial cell development
GO:0002862 IGI negative regulation of inflammatory response to antigenic stimulus
GO:0004602 IMP glutathione peroxidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005739 IMP mitochondrion
GO:0006629 IMP lipid metabolic process
GO:0006641 IMP triglyceride metabolic process
GO:0006749 IEA glutathione metabolic process
GO:0006915 IMP apoptotic process
GO:0006979 IMP response to oxidative stress
GO:0006982 IEA response to lipid hydroperoxide
GO:0007568 IEA aging
GO:0007605 IMP sensory perception of sound
GO:0008283 IMP cell proliferation
GO:0008430 IEA selenium binding
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009410 IMP response to xenobiotic stimulus
GO:0009609 IGI response to symbiotic bacterium
GO:0009611 IMP response to wounding
GO:0009636 IMP response to toxic substance
GO:0009650 IEA UV protection
GO:0009725 IEA response to hormone
GO:0009749 IEA response to glucose
GO:0010269 IEA response to selenium ion
GO:0010332 IGI response to gamma radiation
GO:0014070 IEA response to organic cyclic compound
GO:0014902 IMP myotube differentiation
GO:0017124 IEA SH3 domain binding
GO:0018158 IMP protein oxidation
GO:0032355 IEA response to estradiol
GO:0033194 IMP response to hydroperoxide
GO:0033599 IEA regulation of mammary gland epithelial cell proliferation
GO:0035094 IEA response to nicotine
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0042311 IMP vasodilation
GO:0042542 ISS response to hydrogen peroxide
GO:0042744 IMP hydrogen peroxide catabolic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043295 IEA glutathione binding
GO:0043403 IMP skeletal muscle tissue regeneration
GO:0043523 IMP regulation of neuron apoptotic process
GO:0043534 IMP blood vessel endothelial cell migration
GO:0045444 IMP fat cell differentiation
GO:0045454 IEA cell redox homeostasis
GO:0047066 IEA phospholipid-hydroperoxide glutathione peroxidase activity
GO:0048741 IMP skeletal muscle fiber development
GO:0051450 IMP myoblast proliferation
GO:0051593 IEA response to folic acid
GO:0051702 IGI interaction with symbiont
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0060047 IMP heart contraction
GO:0060055 IMP angiogenesis involved in wound healing
GO:0061136 IEA regulation of proteasomal protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0090201 IEA negative regulation of release of cytochrome c from mitochondria
GO:0097413 IEA Lewy body
GO:1902042 IEA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902176 IMP negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000388829 GPX1P1-001 processed_pseudogene Homo_sapiens 0 608
ENST00000419349 GPX1-002 protein_coding Homo_sapiens 0 375
ENST00000419783 GPX1-001 protein_coding Homo_sapiens 0 632
ENST00000429271 GPX1P2-001 processed_pseudogene Homo_sapiens 0 516
ENST00000496791 GPX1-003 processed_transcript Homo_sapiens 0 261
ENST00000620890 GPX1-201 protein_coding Homo_sapiens 0 614

Loading