C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086374 Cdkn2d-201 ENSMUSG00000096472 10090 - 9:21288463-21291209 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086374
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086374 12.528±1.01 16.542±2.38 9.115±0.63 23.436±7.41 19.235±9.05 13.967±2.41 8.954±0.78 8.610±0.76 25.548±25.32 13.654±2.70 7.750±0.71 10.679±4.15 9.519±4.28 26.178±12.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000493 CIL_000493_0002 CGP 9:21273457-21291209
CIL_000494 CIL_000494_0002 CGP 9:21288463-21312333

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000731 IEA DNA synthesis involved in DNA repair
GO:0004861 IEA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007050 IEA cell cycle arrest
GO:0007605 IMP sensory perception of sound
GO:0008285 IEA negative regulation of cell proliferation
GO:0009411 IEA response to UV
GO:0019901 IEA protein kinase binding
GO:0030308 IEA negative regulation of cell growth
GO:0032526 IEA response to retinoic acid
GO:0033280 IEA response to vitamin D
GO:0042326 IEA negative regulation of phosphorylation
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048102 IEA autophagic cell death
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity
GO:1902230 IEA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000335766 CDKN2D-002 protein_coding Homo_sapiens 0 586
ENST00000393599 CDKN2D-001 protein_coding Homo_sapiens 0 597

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